Cough Clinical Trial - The Effect of Dexmedetomidine for Emergence Cough

Status Completed

Clinical Trial Summary

Dexmedetomidine or remifentanil are effective in attenuating cough during peri-extubation period after general anesthesia. The purpose of this study was to investigate the effect of dexmedetomidine on the remifentanil concentration for the cough suppression during anesthetic emergence.

Clinical Trial Description

Administration of dexmedetomidine before end of surgery could reduce airway reflexes and hemodynamic changes during tracheal extubation. Compared with remifentanil alone, administration of dexmedetomidine in combination with remifentanil is effective in relieving cough and hemodynamic changes without inhibition of respiration. The purpose of this study was to investigate the effect of dexmedetomidine on the remifentanil concentration for the cough suppression during anesthetic emergence using the modified up-and-down method. ;

Study Design

Related Conditions & MeSH terms

Cough

Clinical Trial Details

NCT number	NCT03622502
Study type	Interventional
Source	Ajou University School of Medicine
Contact
Status	Completed
Phase	N/A
Start date	August 16, 2018
Completion date	March 27, 2019

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