Coronary Stenting Clinical Trial
The investigators prospectively studied the effect of aspirin on platelet function in 106 stable outpatients 6 months after successful percutaneous coronary angioplasty. Participants were randomized in a double-blind, double-crossover study (80 or 500 mg per day for 6 months).T
Background:
Acetylsalicylic acid (aspirin) is widely used in the secondary prevention of coronary artery
disease. There is controversy regarding the prevalence of aspirin resistance in patients
with coronary artery disease and the effect of dose on resistance. Our primary aims were to
determine the degree of platelet responsiveness to aspirin, and to study the influence of
dose on platelet inhibition and clinical outcomes after coronary stenting.
;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment
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