Coronary Artery Ectasia Clinical Trial
— NCIPCAEOfficial title:
A New Classification and Interventional Therapy for Coronary Artery Ectasia
This study is aim to present a new classification for coronary artery ectasia and find the best interventional therapy for different types of patients were treated and studied.
Status | Recruiting |
Enrollment | 100 |
Est. completion date | November 30, 2021 |
Est. primary completion date | November 30, 2021 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - Male or non-pregnant female aged =18 years; - Coronary artery ectasia was confirmed by coronary CT or coronary angiography; - The patient (or guardian) is fully aware of the study process and signs the informed consent; - Patients were able to undergo subsequent follow-up. Exclusion Criteria: - Congenital coronary artery fistula; - kawasaki disease; - Treponema pallidum or lyme treponema; - Marfan; - Primary lymphoma; - Coronary artery pseudoaneurysm; - Acute infectious disease or autoimmune disease; - Hematological Disease; - Severe liver and kidney dysfunction (AMI one week later, alanine transaminase =3 times the upper limit of normal value; Creatinine clearance rate =30ml/min or blood creatinine =2.5mg/dl); - Unstable craniocerebral disease; - Cancer; - Severe cognitive impairment (dementia or severe mental illness); - Patients with severe physical disabilities who cannot be followed up regularly; - Other serious uncontrolled systemic diseases; - Female patient who is ready to become pregnant, already pregnant or nursing; - Contraindications to percutaneous coronary intervention (PCI) : for patients at high risk of massive bleeding in the digestive tract, intracranial and other areas, or allergic to contrast agents; - Cannot tolerate dual antiplatelet therapy for at least 1 year; - Age < 18 years old; - Patients who are unable or unwilling to sign informed consent |
Country | Name | City | State |
---|---|---|---|
China | Fuwai Hospital | Beijing | Beijing |
Lead Sponsor | Collaborator |
---|---|
China National Center for Cardiovascular Diseases | Beijing Chao Yang Hospital, Hebei Medical University Fourth Hospital, Peking University People's Hospital |
China,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Major adverse cardiac and cerebral events (MACCEs) | Number of participants with a composite of all-cause mortality, non-fatal myocardial infarction, non-fatal stroke or urgent target vessel revascularization | 6 months after treatment | |
Secondary | Changes in CCS grade | Number of participants with CCS angina pectoris grade aggravated or alleviate | 6 months after treatment | |
Secondary | Changes in drug use | Number of participants with increased the type or dose of anti-myocardial ischemia drugs | 6 months after treatment | |
Secondary | Changes in coronary artery aneurysm diameter | Number of participants with coronary artery aneurysm diameter reduced, increased or unchanged | 6 months after treatment |
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