Coronary Artery Bypass Clinical Trial
Official title:
Postoperative Renal Failure in Cardiac Surgery PMSF-PVC Gradient Study
Acute renal failure is a frequent and severe postoperative complication of cardiac surgery
performed under extracorporeal circulation.
It is an independent risk factor for mortality and significantly increases the length of
hospital stay.
The origin of renal insufficiency after extracorporeal circulation is multifactorial (long
duration of extracorporeal circulation, hemodynamic instability per and post-extracorporeal
circulation, prolonged hypotension, transfusion ...).
Nevertheless, an entirely different pathophysiological mechanism, though not recent, is less
often mentioned but shows renewed interest. This is the concept of renal venous congestion
which may be responsible for impaired renal function in the absence of cardiac dysfunction.
Based on Guyton's circulatory model, the investigators approach this systemic venous
hypertension through the measurement of the Pmsf-PVC gradient.
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