Clinical Trials Logo
  1. Home
  2. Coronary Artery Bypass Graft
  3. NCT00048308

Effect of Pexelizumab on All-Cause Mortality and Myocardial Infarction in Patients Undergoing Coronary Artery Bypass Graft Surgery With Cardio-Pulmonary Bypass

Coronary Artery Bypass Graft Clinical Trial

Clinical Trial Summary

During a heart bypass procedure, a substance called "complement" is released by the body. This complement causes inflammation, which can lead to side effects such as chest pain, heart attacks, heart failure, or impairment of memory, language and motor skills. The purpose of this study is to find out if the study drug (pexelizumab), which blocks complement release, can reduce such side effects and be taken safely.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00048308
Study type Interventional
Source Alexion Pharmaceuticals
Contact
Status Completed
Phase Phase 3
Start date January 2002
View Details
See also
  Status Clinical Trial Phase
Completed NCT01688648 - Comparison Between Lidocaine, Dexmedetomidine, and Their Combined Infusion in Subjects Undergoing Coronary Artery Bypass Graft N/A
Completed NCT01596738 - Tranexamic Acid in On-pump CABG With Premature Clopidogrel Cessation N/A
Completed NCT00965471 - Effect of Chinese Traditional Medicine for Post Revascularization Treatment of Coronary Artery Disease N/A
Completed NCT05058222 - Effect of Deep Breathing Exercises on Post Operative Sleep Duration N/A
Completed NCT03299101 - Pilot Testing a Home-Based Rehabilitation Intervention Designed to Improve Outcomes of Frail Veterans Following Cardiothoracic Surgery N/A
Completed NCT01535222 - Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of MDCO-2010 in Patients Undergoing Elective Coronary Artery Bypass Graft Surgery Phase 2
Completed NCT00863044 - High Frequency Ventilation During Off Pump Coronary Artery Bypass Graft (CABG) Phase 4
Completed NCT01932008 - Evaluation of the Bone Mineral Density and Muscle Mass in Patients Post Coronary Artery Bypass Graft Surgery With Chronic Kidney Disease N/A
Completed NCT05349773 - The Pneumatic Tourniquet Technique for Endoscopic Radial Artery Harvest; Does it Affect Patient Hemodynamics?
Completed NCT03424382 - CREATION Health Readmission Risk Assessment Tool
Not yet recruiting NCT05706545 - Micro- and Macro-Circulation in Cardiac Surgery Patients
Completed NCT01572454 - Comparison of Dexmedetomidine and Remifentanil Infusion During CABG N/A
Completed NCT04993976 - Prehabilitation and Coronary Artery Bypass Grafting N/A
Recruiting NCT01629030 - Risk Factors of Sternal Wound Infection After Coronary Artery Bypass Graft N/A
Completed NCT04310995 - Different Anti-Spastic Therapy Strategies After CABG Using Radial Artery Grafts Phase 4
Completed NCT03925493 - Exercise Prescription in Cardiac Rehabilitation N/A
Not yet recruiting NCT04485143 - Cloud-based ECG Monitoring and Healthcare Model Building on the Population With Coronary Artery Revascularization
Recruiting NCT04231461 - Quality of Life After Cardiac Surgery
Completed NCT03002129 - FLuid Responsiveness Prediction Using EXtra Systoles N/A
Completed NCT01591642 - Physical Activity, Functional Fitness and Quality of Life After Coronary Artery Bypass Grafting N/A