Effect of N-acetylcysteine on Oxidative Stress in COVID-19 Patients

Status Completed

Clinical Trial Summary

The purpose of the study is to assess the potential therapeutic effect of N-acetylcysteine "NAC" in COVID 19 patients.

Clinical Trial Description

This is a phase 3 trial enrolling subjects with newly diagnosed Corona virus disease 2019 ( COVID-19) infection who are classified as moderate cases and require hospitalization. Patients meeting eligibility criteria will be randomized either to receive oral N-acetylcysteine or not along with the institution treatment protocol . Treatment efficacy will be assessed using certain endpoints as follows: 1. Markers of inflammation and oxidative stress 2. Length of hospital stay 3. Need for ventilation 4. Mortality rate ;

Study Design

Related Conditions & MeSH terms

Corona Virus Disease 19 (Covid19)
Corona Virus Infection
Coronavirus Infections
COVID-19
Infections
Severe Acute Respiratory Syndrome
Severe Acute Respiratory Syndrome Coronavirus 2(SARS-CoV2)
Virus Diseases

Clinical Trial Details

NCT number	NCT04792021
Study type	Interventional
Source	Ain Shams University
Contact
Status	Completed
Phase	Phase 3
Start date	March 9, 2021
Completion date	April 1, 2022

View Details

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