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Clinical Trial Summary

The primary purpose of this trial is to evaluate the safety and tolerability of ranibizumab given via subconjunctival injection in patients undergoing corneal transplantation.


Clinical Trial Description

As a secondary objective, this study also aims to establish the corneal and anterior chamber concentration of ranibizumab when delivered subconjunctivally at the limbus in patients undergoing corneal transplantation. The effects of ranibizumab on corneal epithelial healing will be examined following adjunctive use in corneal transplantation. Finally, clinical characteristics including recurrent corneal neovascularization will be studied. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT00769145
Study type Interventional
Source University of Miami
Contact
Status Completed
Phase Phase 1
Start date October 2008
Completion date March 2012

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