To Compare the Progressive Cracking Technique and Conventional Chop Technique on Corneal Endothelial Cells in Patients With Hard Nucleus Cataract

Corneal Endothelial Cell Clinical Trial

Official title:

To Compare the Progressive Cracking Technique and Conventional Chop Technique on Corneal Endothelial Cells in Patients With Hard Nucleus Cataract

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT04828499
• Other study ID #: WDD-hard-nucleus cataract
• Status: Recruiting
• Phase: N/A
• Start date: January 1, 2017
• Est. completion date: June 30, 2021

Study information

• Verified date: March 2021
• Source: Wenzhou Medical University
• Contact: Dandan Wang
• Phone: 18258227706
• Email: wangdan4827716[@]yahoo.com.cn
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Approximately 60 participants at Eye Hospital of Wenzhou Medical University during January,2017 to June 2021 will be enroll in our study. And dived them randomly into 2 groups:Progressive Cracking Technique (30 eyes) and Conventional Chop Technique (30 eyes) .

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 60
• Est. completion date: June 30, 2021
• Est. primary completion date: June 30, 2021
• Accepts healthy volunteers: No
• Gender: All
• Age group: 60 Years to 90 Years

Eligibility

Inclusion Criteria:

• Cataract with Grade IV~V nucleus sclerosis

• Cataract surgery is planned

• The operation was successful without any complications

Exclusion Criteria:

• Patients with other diseases that affect the corneal endothelium

• Has a history of anterior segment surgery

• Failure to cooperate with follow-up

Related Conditions & MeSH terms

• Cataract
• Corneal Endothelial Cell
• Hard Nuclear Cataract
• Progressive Cracking Technique

Intervention

Procedure:
• Progressive Cracking Technique
Performing the cataract surgery with our phaco chop-progressive cracking technique.
• Conventional Chop Technique
Performing the cataract surgery with Conventional Chop Technique.

Locations

Country	Name	City	State
China	Eye Hospital of Wenzhou Medical College	Wenzhou	Zhejiang

Sponsors (1)

Lead Sponsor	Collaborator
Yune Zhao

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	corneal endothelial cell density	the number of corneal endothelial cells per unit area.	up to 1 months
Primary	Coefficient of variation of endothelial cells	represents the variation coefficient of cell area	up to 1 months
Primary	percentage of hexagonal cells of the cells marked	represents the percentage of hexagon cells,the ideal value is above 50%	up to 1 months
Primary	central corneal thickness	thickness in micrometer	up to 1 months