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NCT05045053 Clinical Trial

Efficacy of Xiidra in Dry Eye Disease After Collagen Cross Linking

Corneal Disease Clinical Trial

Official title:
Efficacy of Xiidra in the Management Dry Eye Disease After Corneal Collagen Cross Linking

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT05045053
Other study ID # Hamaky17
Secondary ID
Status Recruiting
Phase Phase 4
First received
Last updated
Start date February 1, 2021
Est. completion date January 2022

Study information
Verified date September 2021
Source Benha University
Contact Tarek R Elhamaky, M.D.
Phone +971 503207889
Email dr_thamakyy@yahoo.com
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

dry eye disease after corneal collagen cross linking affect ocular function leading to reduced vision, photophobia, glare, halos, and foreign body sensation.

Description:

first group of patients were treated with 0.5 % xiidra twice daily and artificial tears for 6 months.Second group treated with artificial tears for 6 months. the treatment starts after corneal collagen cross linking in both groups ,Baseline and post-treatment full ophthalmic examination was done.

Recruitment information / eligibility
Status Recruiting
Enrollment 40
Est. completion date January 2022
Est. primary completion date January 2022
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - corneal collagen cross linking Exclusion Criteria: - systemic or ocular diseases ,previous ocular surgery, corneal pathology and contact lens wearers

Study Design

Related Conditions & MeSH terms

Intervention

Drug:
• Xiidra 5% Ophthalmic Solution
lifitegrast 0.5% ia applied twice daily after corneal collagen cross linking

Locations
Country Name City State
United Arab Emirates INMC Abu Dhabi

Sponsors (1)
Lead Sponsor Collaborator
Benha University

Country where clinical trial is conducted

United Arab Emirates, 

Outcome
Type Measure Description Time frame Safety issue
Primary Change in Break up Time fluorescein sodium stripes will be used for measurement of Break up Time in seconds at baseline and during the study 6 months
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