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Cornea clinical trials

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NCT ID: NCT04066439 Recruiting - Cornea Clinical Trials

The Marker Expression of Corneal Surface From Penetrating Keratopathy After Collagenase A Assisted COMET Case Series

Start date: August 1, 2019
Phase:
Study type: Observational

In order to examine the cells of the corneal epithelium in the patients who receive corneal transplantation after collagenase A assisted cultivated oral mucosa epithelium transplant (CA-COMET), we analyzed the specimens from penetrating keratoplasty with immunochemical staining.

NCT ID: NCT03906513 Completed - Cornea Clinical Trials

Evaluation of the Efficacy of OMK2 in Recovering Corneal Neural Damage in Patients With Diabetes

Start date: May 3, 2017
Phase: N/A
Study type: Interventional

This will be a single-centre, randomized, pilot study. 30 patients with diabetes who previously had received Argon laser photocoagulation will be enrolled.

NCT ID: NCT03674892 Terminated - Cornea Clinical Trials

Intranasal Neurostimulation in Ameliorating Symptoms of Neuropathic Corneal Pain

INSTANT
Start date: September 28, 2018
Phase: N/A
Study type: Interventional

This study is a prospective, interventional, open-label, single arm, non-randomized trial treating 30 patients with peripheral or mixed neuropathic corneal pain at their baseline exam and following 45 days and 90 days of daily use with the TrueTearâ„¢ ITN device.

NCT ID: NCT03655743 Completed - Refractive Errors Clinical Trials

PRO Measure for Refractive Surgery IRAS Project Number 246072

Start date: August 31, 2018
Phase:
Study type: Observational [Patient Registry]

The development and validation of a concise, practical, on-line, self-administered, self-archiving, and self-scoring PRO questionnaire for routine clinical use in refractive surgery is the primary study objective. Secondary objectives are to gather outcome data from patients before and after surgery in each of the following domains comprising key elements of vision related quality of life: spectacle dependence; quality of vision; eye comfort; freedom; emotional well-being; and overall satisfaction with the results of surgery. Patients undergoing refractive surgery at Moorfields Private Outpatient Clinic will be enrolled in the study in the validation phase.

NCT ID: NCT03518775 Completed - Cornea Clinical Trials

Repeatability and Reproducibility of the IOLMaster 700 Vers 1.70 and Agreement With IOLMaster 700 Vers. 1.50 and Pentacam

Start date: March 16, 2018
Phase:
Study type: Observational

The objectives of this study are to determine the agreement of measurements between the IOLMaster 700 SW Vers. 1.70 and IOLMaster 700 SW Vers. 1.50 and Pentacam, as well as to evaluate the repeatability and reproducibility of the IOLMaster 700 SW Vers 1.70. The following parameters will be evaluated for Total Keratometry, (TK) and Posterior Corneal Surface (PCS): - cylinder (CYL), Axis (A) - spherical equivalent (SE) Specific Objectives: 1. To compare the agreement of SE between IOLMaster 700 SW Vers. 1.70 and IOLMaster 700 SW Vers. 1.50 (Carl Zeiss Meditec AG, Jena, Germany) 2. To compare the agreement of Cylinder magnitude and axis between IOLMaster 700 SW Version 1.70 and Pentacam 3. To evaluate the repeatability and reproducibility of the IOLMaster 700 SW Vers. 1.70 for all measurement parameters listed above

NCT ID: NCT03299530 Recruiting - Astigmatism Clinical Trials

Accuracy of Corneal Astigmatism in Different Region Modes

Start date: October 10, 2017
Phase:
Study type: Observational

To analyze the difference between measured total corneal astigmatism and actual corneal astigmatism under different region modes and optimize the region setting.

NCT ID: NCT03230981 Completed - Cornea Clinical Trials

Age-dependency of Cornea Biomechanics Using OCT Vibrography

Start date: August 1, 2019
Phase: N/A
Study type: Interventional

The aim of this pilot study is to assess the ability of a new optical coherence tomography system to obtain information on biomechanics of the cornea.

NCT ID: NCT03127163 Completed - Keratoconus Clinical Trials

Intraestromal Corneal Ring in Mild Keratoconus

Start date: January 10, 2015
Phase: N/A
Study type: Interventional

To determine whether the implantation of an intrastromal corneal ring is an effective treatment for a homogeneous group of mild keratoconus patients.

NCT ID: NCT03010748 Recruiting - Cornea Clinical Trials

Multi-center Clinical Trial on Corneal Morphology Analysis in Chinese Population

Start date: November 2015
Phase:
Study type: Observational

Based on the corneal morphometry instrumentation Oculus Pentacam, which is commonly used before and after clinical refractive surgery, we will collect the corneal morphological and biologic parameters of the population under refractive surgery screening in refractive surgery centers around the country, and construct corneal morphology database in different living areas of Chinese people. Based on this, compared with the suspected keratoconus and keratoconus population, the screening criteria and reference standards accord with the characteristics of keratoconus of Chinese ethnic will be achieved.

NCT ID: NCT03006211 Completed - Cornea Clinical Trials

The Effects of Nitrogen Protoxide and Oxygen on Corneal Endothelial in Pediatric Patients

Start date: December 2016
Phase: N/A
Study type: Interventional

To evaluate the mean changes in Endothelial Cell and Corneal pachymetry in eyes that operated under N2O + sevoflurane and O2 + sevoflurane general anesthesia.