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Effects of Endoscopic Lung Volume Reduction on Diaphragm Function and Conformation

COPD Clinical Trial

Official title:
Effects of Endoscopic Lung Volume Reduction on Diaphragm Function and Conformation

Clinical Trial Summary

Chronic obstructive lung disease (COPD) is a common disease that is frequently complicated by hyperinflation. The resulting increase in lung volume impairs the diaphragmatic function because of a shortening of the diaphragmatic fibers and an increase in the radius of curvature of the diaphragmatic domes. Lung volume reduction surgery (LVRS) has already shown an improvement in diaphragmatic function that could be explained by a change of the diaphragm conformation. More recently, endoscopic lung volume reduction (ELVR) has shown benefits in terms of respiratory function, exercise capacity and quality of life, but the mechanisms of these improvements are poorly understood. Therefore, we aim to evaluate the evolution of the diaphragmatic function and the changes in diaphragmatic conformation after unilateral ELVR.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05799352
Study type Interventional
Source Erasme University Hospital
Contact Olivier Taton
Phone 025553943
Email olivier.taton@hubruxelles.be
Status Recruiting
Phase N/A
Start date April 1, 2019
Completion date December 2023
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