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Revefenacin in Acute Respiratory Insufficiency in COPD — RARICO  

COPD Clinical Trial

Official title:
Revefenacin in Acute Respiratory Insufficiency in COPD (RARICO)

Clinical Trial Summary

RARICO is a pragmatic, randomized, controlled, double-blinded, multi-center trial evaluating the safety and feasibility of nebulized revefenacin in comparison to nebulized ipratropium in patients with COPD and acute respiratory failure requiring invasive mechanical ventilation.

Clinical Trial Description

Objective: To assess the efficacy of nebulized revefenacin in improving the lung mechanics of COPD patients with acute respiratory failure requiring invasive mechanical ventilation (MV), in comparison to a control group receiving the short-acting muscarinic antagonist ipratropium. Hypothesis: Revefenacin is as efficacious as ipratropium in improving the lung mechanics of COPD patients with acute respiratory failure. Study Design: RARICO is a pragmatic, randomized, controlled, double-blinded, multi-center trial evaluating the safety and feasibility of nebulized revefenacin in comparison to nebulized ipratropium in patients with COPD and acute respiratory failure requiring invasive mechanical ventilation. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04315558
Study type Interventional
Source University of California, Los Angeles
Contact Leslie Cortes
Phone 3102063669
Email LeCortez@mednet.ucla.edu
Status Recruiting
Phase Phase 2
Start date November 1, 2020
Completion date June 30, 2024
View Details
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