HFNC vs NPPV After Early Extubation for Patients With COPD

Status Recruiting

Clinical Trial Summary

High-flow nasal cannula oxygen therapy(HFNC) has proved no significant difference compared with noninvasive positive pressure ventilation (NPPV) in preventing postextubation respiratory failure and reintubation in patients with acute hypoxemic respiratory failure.However, the efficacy of early postextubation sequential HFNC in COPD patients with hypercapnic respiratory failure is inconclusive.

Clinical Trial Description

The investigators conducted this prospective randomized controlled trial to explore the efficacy, safety of HFNC versus NPPV after early extubation in COPD patients with hypercapnic respiratory failure.The investigators hypothesized that the efficacy of HFNC after early extubation is non-inferior to that of NPPV. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04156139
Study type	Interventional
Source	Chinese PLA General Hospital
Contact	Han Xiaobo, MD
Phone	+86 18600310765
Email	hansir510@163.com
Status	Recruiting
Phase	N/A
Start date	December 18, 2019
Completion date	November 1, 2022

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