COPD Clinical Trial
Official title:
Effect of Exercise Training on Inflammatory Mediators in COPD
Verified date | December 2019 |
Source | Faculty of Medicine, Sousse |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
Chronic obstructive pulmonary disease (COPD) is widely spread all over the world. It is predicted to be the third leading cause of death by 2020[1]. COPD is a common, preventable treatable disease that is characterized by an airflow limitation which is not fully reversable[2].
Status | Completed |
Enrollment | 28 |
Est. completion date | April 27, 2019 |
Est. primary completion date | April 17, 2019 |
Accepts healthy volunteers | No |
Gender | Male |
Age group | 40 Years to 75 Years |
Eligibility |
Inclusion Criteria: - COPD diagnosed by pulmonary function testing - Clinically stable - Abscence of other obstructive diseases - Signed written consent Exclusion Criteria: - Neuromuscular diseases -Severe psychiatric, neurologic or musculoskeletal conditions and /or instable--- -- - cardiovascular diseases. - Contre-indications to physical therapy - Acute exacerbations a month before the intervention |
Country | Name | City | State |
---|---|---|---|
Tunisia | Amal Acheche | Sousse |
Lead Sponsor | Collaborator |
---|---|
Faculty of Medicine, Sousse |
Tunisia,
authors non mentionned., global initiative for chronic lung disease. 2017
Barnes PJ. Cellular and molecular mechanisms of chronic obstructive pulmonary disease. Clin Chest Med. 2014 Mar;35(1):71-86. doi: 10.1016/j.ccm.2013.10.004. Epub 2013 Dec 12. Review. — View Citation
Barnes PJ. Inflammatory mechanisms in patients with chronic obstructive pulmonary disease. J Allergy Clin Immunol. 2016 Jul;138(1):16-27. doi: 10.1016/j.jaci.2016.05.011. Epub 2016 May 27. Review. — View Citation
Molfino NA, Jeffery PK. Chronic obstructive pulmonary disease: histopathology, inflammation and potential therapies. Pulm Pharmacol Ther. 2007;20(5):462-72. Epub 2006 May 6. Review. — View Citation
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---|---|---|---|---|
Primary | Enzyme linked immunosorbent assay for serum cytokines levels change | The interleukines were determined by ELISA assays with commercial kits | Baseline, 6 months |
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