Bronchiectasis Effect in COPD Patients

Copd Clinical Trial

Official title:

Effect of Bronchiectasis on Respiratory Functions, Exercise Capacity, Dyspnea Perception and Quality of Life in COPD Patients

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03670940
• Other study ID #: IKC
• Status: Completed
• Start date: January 2015
• Est. completion date: April 2018

Study information

• Verified date: September 2018
• Source: Izmir Katip Celebi University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The etiology of bronchiectasis, known as permanent, abnormal, and localized development of bronchi, varies. However, most of them are responsible for infections during childhood. The prevalence of bronchiectasis is particularly high in advanced COPD patients. This phenomenon, called COPD-bronchiectasis overlap syndrome, affects the clinic of COPD patients negatively. In this study; bronchiectasis in respiratory function, exercise capacity, dyspnoea and quality of life in COPD patients.

Description:

The etiology of bronchiectasis, known as permanent, abnormal, and localized development of bronchi, varies. However, most of them are responsible for infections during childhood. The prevalence of bronchiectasis is particularly high in advanced COPD patients. This phenomenon, called COPD-bronchiectasis overlap syndrome, affects the clinic of COPD patients negatively. In this study; bronchiectasis in respiratory function, exercise capacity, dyspnoea and quality of life in COPD patients.

Torax CTs of patients with COPD who are admitted to the outpatient clinic will be examined. There will be two groups, group 1 in patients with COPD accompanied by bronchiectasis and group 2 in COPD patients without bronchiectasis. In both groups, respiratory function tests, exercise capacities, dyspnea perceptions and quality of life will be evaluated. The data will be compared between the two groups.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 35
• Est. completion date: April 2018
• Est. primary completion date: March 2018
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• above 18 years old

• clinically stable

Exclusion Criteria:

• other respiratory disease

Related Conditions & MeSH terms

• Bronchiectasis
• Copd

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Izmir Katip Celebi University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Exercise capacity	six minute walk test	15 minutes
Secondary	Dyspnea Severity	mMRC Dyspnea Scale (0: no dyspnea, 4: very severe dyspnea)	5 minutes
Secondary	Lung Function	Respiratory Function Test	20 minutes
Secondary	Health Related Quality of Life	St. George Respiratory Questionnaire (maximum score: 100, lower score means better quality of life)	25 minutes