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NCT00965029 Clinical Trial

Spirometry in Mechanically Ventilated Chronic Obstructive Pulmonary Disease (COPD) Patients

COPD Clinical Trial

Official title:
Spirometry in Mechanically Ventilated COPD Patients: Correlation of Lung Function Tests to Successful Weaning From Mechanical Ventilation

Clinical Trial Details — Status: Not yet recruiting

Administrative data
NCT number NCT00965029
Other study ID # 101/09
Secondary ID
Status Not yet recruiting
Phase N/A
First received August 24, 2009
Last updated April 4, 2011
Start date September 2009
Est. completion date September 2012

Study information
Verified date August 2009
Source Assaf-Harofeh Medical Center
Contact Arie Soroksky, MD
Phone 972-8-9779320
Email soroksky@gmail.com
Is FDA regulated No
Health authority Israel: Ethics Commission
Study type Observational

Clinical Trial Summary

Patients with COPD who deteriorate to Respiratory Failure pose a challenge to the intensivist both in ventilating an obstructed patient and in weaning from mechanical ventilation.

Currently there are no accepted extubation criteria in COPD patients that could predict successful weaning from mechanical ventilation. In this study we will attempt to correlate spirometric data to eventual weaning from mechanical ventilation.

Description:

COPD patients who deteriorate to Respiratory Failure will be recruited. Sedation will be interrupted daily, and each day once the patient is awake and cooperative, spirometry will be performed. FEV1 and FVC will be recorded and later correlated to eventual rate of successful extubation.

Recruitment information / eligibility
Status Not yet recruiting
Enrollment 100
Est. completion date September 2012
Est. primary completion date September 2012
Accepts healthy volunteers No
Gender Both
Age group 18 Years and older
Eligibility Inclusion Criteria:

- >18

- Mechanically ventilated due to COPD exacerbation

Exclusion Criteria:

- decreased level of consciousness

- uncooperative patient

- Bronchial asthma

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

  • COPD
  • Pulmonary Disease, Chronic Obstructive

Locations
Country Name City State
Israel Arie Soroksky Beer Yaakov Zerifin

Sponsors (1)
Lead Sponsor Collaborator
Assaf-Harofeh Medical Center

Country where clinical trial is conducted

Israel, 

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