Project to Improve the Diagnosis and Treatment Ability of Adult Severe Community Acquired Lower Respiratory Tract Infection

COPD Exacerbation Clinical Trial

Official title:

Project to Improve the Diagnosis and Treatment Ability of Adult Severe Community Acquired Lower Respiratory Tract Infection

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04959955
• Other study ID #: LM2016057
• Status: Completed
• Start date: August 8, 2015
• Est. completion date: December 12, 2019

Study information

• Verified date: July 2021
• Source: Peking University Third Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

1. Objective to understand the proportion of atypical pathogens in the pathogens of SCAP and AECOPD in urban hospitals in China.

2. Objective to investigate the antimicrobial resistance of atypical pathogens in patients with acute exacerbation of chronic obstructive pulmonary disease (COPD) and SCAP in urban hospitals.

3. Objective to master the important clinical characteristics of patients with acute exacerbation of SCAP and COPD caused by atypical pathogens and mixed infection in urban hospitals in China, and to put forward the experience judgment index.

4. Objective to evaluate the advantages of various diagnostic methods for atypical pathogens causing lower respiratory tract infection.

5. It is suggested that the current empirical treatment of SCAP and severe COPD in China should be improved.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 200
• Est. completion date: December 12, 2019
• Est. primary completion date: July 10, 2016
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• SCAP

• AECOPD

Exclusion Criteria:

• Pregnant or lactating women.

• Patients with bronchiectasis.

• Patients with active pulmonary tuberculosis.

• Aspiration pneumonia or obstructive pneumonia.

• Two weeks before the onset of hospital treatment history, this infection can not be excluded from hospital acquired infection.

• HIV positive patients (but HIV testing is not required).

• Patients who are unable and / or unable to understand and / or implement the investigation protocol.

Related Conditions & MeSH terms

• CAP
• COPD Exacerbation
• Respiratory Tract Infections

Locations

Country	Name	City	State
n/a

Sponsors (2)

Lead Sponsor	Collaborator
Peking University Third Hospital	First Hospital of China Medical University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Incidence of atypical pathogens and mixed infections	Incidence of atypical pathogens and mixed infections	2year Incidence