Disparities in Emergency Contraceptive Metabolism Dictate Efficacy

Status Recruiting

Clinical Trial Summary

The purpose of this study is to learn more about why some people are at greater risk for oral emergency contraceptive failure while others are not. The investigators want to learn if genetic differences impact the risk of emergency contraception failure.

Clinical Trial Description

Each of us can respond differently to a drug or medication based on our genetics. An emergency contraceptive, ulipristal acetate or UPA, normally works by stopping or delaying the ovary from releasing an egg (ovulation). Our bodies break down UPA in order to use it through a system call the cytochrome P450 pathway but this pathway can be faster or slower depending on our genetics. The investigators want to learn more about how our individual genetic differences in this pathway change how the ovary responds to UPA. The overall goal of this research is to improve the effectiveness of emergency contraception for all people. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05674513
Study type	Interventional
Source	Oregon Health and Science University
Contact	Women's Health Research Unit Department of OB/GYN
Phone	503-494-3666
Email	whru@ohsu.edu
Status	Recruiting
Phase	Phase 4
Start date	January 9, 2023
Completion date	December 31, 2027

View Details

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