Effects of Oral Contraceptives on DNIC in Non-painful Healthy Women

Status Completed

Clinical Trial Summary

The purpose of this study is tu assess the influence of oral contraceptives (OC) on diffuse noxious inhibitory control (DNIC) in healthy women, tested during high, low endogenous estrogens sessions and ovulatory period.

Clinical Trial Description

After being informed about the study and it protocol, all patients giving written informed consent, will undergo to a cephalic (masseter) and extracephalic (finger) mechanical stimulus to evaluate the threshold of mechanical pain, and physiological records of systolic/diastolic pressure and heart rates. After, we will evaluate the threshold response and physiological rates to the same mechanical stimulus under a thermal (cold) conditional pain (TCP) at 3 different moments of menstrual period in No contraceptive group (No OC) versus Contraceptive group (CO). Finally, we will compare the mechanical threshold response, physiological rates and pain perception between both groups. ;

Study Design

Related Conditions & MeSH terms

Contraceptive Usage
Diffuse Noxious Inhibitory Control

Clinical Trial Details

NCT number	NCT04365426
Study type	Interventional
Source	Universidad Vina del Mar
Contact
Status	Completed
Phase	N/A
Start date	April 24, 2020
Completion date	August 30, 2021

View Details

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