Novel Topical Treatment of Hand Dermatitis (Eczema)

Status Completed

Clinical Trial Summary

This study is designed as a prospective, randomized, double-blind right/left comparison of Epikeia coatings to improve hand dermatitis.

Clinical Trial Description

Hand dermatitis was chosen for investigation due to high incidence and typical symmetrical involvement that allows for right/left treatment comparisons. Hand dermatitis is also important due to its implication on healthcare workers in particular, where frequent hand washing and chronic occlusion from gloving, provide a route for skin sensitization to natural rubber latex proteins increase the risk of colonization of microorganisms on the skin, and thereby increase the likelihood of contact dermatitis.

This feasibility study will be performed to evaluate the efficacy of PVDF coatings in treating chronic hand dermatitis. ;

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT00614289
Study type	Interventional
Source	Biomedical Development Corporation
Contact
Status	Completed
Phase	Phase 1
Start date	August 2006
Completion date	July 2009

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT00371163` - Molecular and Cellular Characterization of Spongiotic Dermatitis	N/A
Completed	`NCT02028208` - Clinical Evaluation of Metal Panel Allergens: Mercury, Aluminum and Palladium Dose Response Study	Phase 2
Not yet recruiting	`NCT04853823` - A Safety, Tolerability, and Dermal Reactogenicity Study of PDC-APB	Phase 1
Recruiting	`NCT06387472` - DermAI to Evaluate Human Factor of Testing	N/A
Completed	`NCT02700373` - A Phase I, Single-Center Study of PDC-APB in Healthy Volunteers	Phase 1
Completed	`NCT03089775` - Evaluation of Safety and Efficacy of BBI-2000 in Treating and Preventing Contact Dermatitis	Phase 1
Completed	`NCT04438135` - Children With Aluminium Contact Allergy: Cutaneous Exposure Study	N/A
Recruiting	`NCT06189144` - Testing an Intervention in Irritative Contact Dermatitis	N/A
Completed	`NCT04921163` - Children With Aluminium Contact Allergy: Oral Exposure Study	N/A
Not yet recruiting	`NCT02026700` - Bariederm Cream in Chronic Contact Dermatitis	N/A
Completed	`NCT02028182` - Clinical Evaluation of Lyral® Dose Response Study	Phase 2
Completed	`NCT00824889` - Exploratory Study of Natural Killer Cells in Human Skin	N/A
Completed	`NCT00646867` - Effect of Tetrix on Alleviation of Burning,Itching Associated With Lesions of Contact Dermatitis	N/A
Withdrawn	`NCT01518348` - Clinical Evaluation of T.R.U.E. TEST Panel 3.2 in Children and Adolescents	Phase 3
Recruiting	`NCT03705182` - Prevention of Dermatitis in Epoxy Exposed Workers	N/A
Terminated	`NCT03198390` - Linking Epidermal Barrier Function With Anti-Oxidant Defense Mechanisms in Skin Conditions
Recruiting	`NCT06331390` - Assessment of Niacinamide Cosmetic Product Efficacy in Model of Irritant Contact Dermatitis	N/A
Completed	`NCT00640614` - Clinical Evaluation of T.R.U.E. TEST® : Safety and Efficacy	Phase 3
Completed	`NCT00640250` - Clinical Evaluation of T.R.U.E. TEST® Panel 3.2 Allergens: Dose Response	Phase 2
Recruiting	`NCT06177314` - Molecular Diagnosis of Allergic Contact Dermatitis