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Effects of Alpha-1 Antagonist, Stress and Relaxation on Anorectal Functions

Constipation Clinical Trial

Official title:
Effect of Stress and a Alpha-1 Antagonist on Anorectal Functions

Clinical Trial Summary

This study is designed to better understand the effects of effects of stress, relaxation, and a medication alfuzosin on bowel control and emptying in healthy people and patients with bowel problems.

Clinical Trial Description

Normally, bowel emptying requires relaxation of the anal sphincter (i.e., lowermost end of intestinal tract) and pelvic muscles. Some people cannot relax these muscles normally and experience constipation. Alfuzosin is a medication which is approved to treat bladder but not bowel problems. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01834729
Study type Interventional
Source Mayo Clinic
Contact
Status Completed
Phase Phase 2
Start date March 2013
Completion date September 6, 2017
View Details
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