Constipation Clinical Trial
Official title:
The Efficacy and Safety Study of Electro-acupuncture for Severe Chronic Functional Constipation - a Multi-center, Randomized Controlled Trial
The main purpose of this study is to evaluate efficacy of electro-acupuncture for severe functional constipation compared with sham acupuncture, used as placebo; the secondary purpose is to evaluate the safety and post-treatment effect of electro-acupuncture.
Chronic functional constipation is a common disease. To date there has not specific therapy
on chronic functional constipation. Systematic reviews indicate that acupuncture is probably
effective for the disease, but the evidence is limited. Recently, we have finished a
multi-center clinical trial of individualized deep electro-acupuncture (EA) for chronic
functional constipation (n=460, Registration ID: NCT00508482) which preliminarily showed EA
was effective.
This multi-center large-sample randomized controlled clinical trial of acupuncture for
severe functional constipation is designed to confirm the efficacy and safety of EA.
This project is conducted by Chinese experts, supported by the Chinese Government. The
research result is expected to provide high quality evidence of EA for chronic functional
constipation.
;
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Treatment
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