Constipation Clinical Trial
Official title:
Comparative Study Between Surgical and Non Surgical Treatment of Anismus in Patients With Symptoms of Obstructed Defecation
Comparative study between surgical and non surgical treatment of anismus in patients with
symptoms of obstructed defecation.
Anismus is a significant cause of chronic constipation. This study came to compare the
results of BFB training , BTX-A injection and PDPR in the treatment of anismus patients.
Patients and methods: Seventy two anismus patients fulfilled Rome II criteria for functional
constipation were included in this study. All patients underwent anorectal manometry,
balloon expulsion test, defecography, and electromyography activity of the EAS. All patients
had non relaxing puborectalis muscle.. The patients were randomized into three groups. Group
I patients received biofeedback therapy, two times per week for about 1 month. Group II
patients were injected with BTX- A. Group 111 partial division of puborectalis was done.
Follow up was conducted weekly in the first month then monthly for about 1 year.
Key words:
Obstructed defecation, chronic constipation, puborectalis, pelvic floor
;
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment
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