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Oscillatory Acoustic-electric Stimulation in Patients With Disorders of Consciousness

Consciousness Disorder Clinical Trial

Official title:
Acoustic-electric Therapy in Patients With Disorders of Consciousness

Clinical Trial Summary

Altered gamma activity has been observed in several neurological and psychiatric disorders, including a reduction in gamma synchronization in patients with disorders of consciousness. Modulation of gamma oscillations with rhythmic stimulation has been used as a possible therapeutic tool. Hence, we try to use acoustic and electric stimulation at gamma frequency to restore brain oscillation and thereby to improve conscious awareness in patients with disorders of consciousness.

Clinical Trial Description

We propose a matched-pair parallel study in patients with disorders of consciousness to investigate whether combined acoustic and trigeminal nerve stimulation can modulate brain oscillations, as measured by electroencephalography (EEG), and whether the brain activity changes are coupled with improvements in consciousness. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04435301
Study type Interventional
Source First Affiliated Hospital of Zhejiang University
Contact
Status Completed
Phase N/A
Start date June 20, 2020
Completion date September 20, 2021
View Details
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