Contribution of PRF in CDH in Children With Prothetic Patch Closure — HECODIAP  

Congenital Diaphragmatic Hernias Clinical Trial

Official title: Contribution of PRF (Platelet Rich Fibrin) in the Biological Functionalization of Prothetic Patch Closure : in Vitro Study

Status Terminated

Clinical Trial Summary

Improved management of giant congenital diaphragmatic hernias (CDH) in neonates : decreased risk of morbidity and mortality due to prosthesis release. CDH is a rare disease with a still very dark prognosis, with a high rate of morbidity and mortality in giants forms linked to the release of insufficiently biologically integrated prosthesis. The biological functionalization of the prosthetic materials by host PRF would improve the biological colonization of materials and thus reduce the risk of prosthetic release.

Clinical Trial Description

n/a

Related Conditions & MeSH terms

• Congenital Diaphragmatic Hernias
• Hernia, Diaphragmatic
• Hernias, Diaphragmatic, Congenital

• NCT number: NCT03861182
• Study type: Interventional
• Source: University Hospital, Strasbourg, France
• Status: Terminated
• Phase: Phase 3
• Start date: September 12, 2019
• Completion date: December 10, 2019