Congenital Cataract Clinical Trial
Official title:
Comparison of Traditional Cataract Surgery and Traditional Surgery Combine Triamcinolone Staining of the Anterior Vitreous in Treating Congenital Cataracts
Previously, the investigators have developed a surgical technique to reduce inflammatory response after congenital cataract surgery. This prospective, randomized controlled study aims to compare the prognosis of traditional cataract surgery with traditional surgery combined triamcinolone staining of the anterior vitreous in treating congenital cataracts.
Surgical technique for congenital cataract is now more and more mature, but many young
patients still have obvious postoperative inflammatory response, which might cause visual
axial opacification, posterior synechiae and secondary glaucoma. Triamcinolone is used in
intraocular injection for its anti-inflammatory effect However, the application of
Triamcinolone was reported to be associated with high intraocular pressure. It is necessary
to evaluate the safety and effectiveness of using triamcinolone in congenital cataract
surgery.
In this randomized clinical trial, children with equal degree of congenital cataract in both
eyesare enrolled. Patients receive cataract surgery on both eyes on the same day. For each
patient, one eye is randomly assigned to undergo traditional surgical procedure, while the
fellow eye is undergoing new surgical procedure. The traditional surgical procedure include
anterior continuous curvilinear capsulorhexis (ACCC), irrigation/aspiration (I/A), posterior
continuous curvilinear capsulorhexis (PCCC), and anterior vitrectomy(A-VIT). Primary
intraocular lens implantation (IOL) is performed in children older than age of two. The new
surgical procedure is to combine triamcinolone staining of the anterior vitreous on the basis
of the traditional surgical procedure. Investigators then compare the incidence of high
intraocular pressure, visual axis opacification, uveitis, iris/pupil abnormality, and macular
edema between two groups
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