Congenital Cataract Clinical Trial
Official title:
Expression Profile of Inflammatory Cytokines in Congenital Cataract After Lensectomy and Anterior Vitrectomy
In this prospective study , a cohort of 58 eyes with congenital cataract from Wenzhou medical university was erolled.33 eyes with congenital cataract was after lensectomy and anterior vitrectomy as post-surger group, 26 eyes without cataract surgery as control group. The cytokines of MCP-1, VEGF, IL-1, IFN-γ, IL-1r,IL-4,IL-17, IL-2,IL-5,G-CSF,IL-12, IL-15 was evaluated
Secondary IOL implantation in aphika children and lensectomy and anterior vitrectomy and
primary IOL implantation in children with congenital cataract were both performed by the same
surgeon(Z.Y.E) and videos were collected to review the capsular reconstruction condition and
lens implantation position.
Aqueous humor (100-200 μl) was aspirated from each patient before the surgery. The research
was to evaluate the relationship between the cytokine profile in aqueous humor and the state
of capsule after Lensectomy and Anterior Vitrectomy.Aqueous humor was obtained , Human
Magnetic Luminex Screening Assay was used to determine the aqueous humor levels of cytokines.
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