Cerebral Computed Tomography on Patients With Minor Head Injuries

Computed Tomography Clinical Trial

Official title:

Use of Cerebral Computed Tomography on Patients With Minor Head Injuries in a Danish Emergency Department: A Retrospective Cohort Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT06399913
• Other study ID #: UNIFY
• Status: Completed
• Start date: January 1, 2023
• Est. completion date: January 30, 2024

Study information

• Verified date: April 2024
• Source: University of Southern Denmark
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

This observational study aims to calculate the prevalence of conditions or diseases requiring immediate medical attention in CTC scans with an indication of bleeding post trauma performed in the ED at Odense University Hospital. Secondary, we aim to evaluate the Scandinavian Neurotrauma Committee clinical guideline 2013 for minor head injury.

Description:

In this retrospective study, our primary objectives are threefold: first, to calculate the prevalence of conditions or diseases requiring immediate medical attention and to subdivide them to explore potential correlations with biochemical, clinical, and patient baseline variables using multiple regression analysis. Secondly, we wanted to analyze our use of SNC CPG and evaluate if a more stringent application could reduce the potentially unnecessary overuse of CTC. Lastly, we aim to evaluate the 30-day mortality and readmission rates to a hospital following CTC performed in the ED.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 7106
• Est. completion date: January 30, 2024
• Est. primary completion date: December 31, 2023
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• CTCs conducted from 01.01.2023 to 31.12.2023 in the ED

Exclusion Criteria:

• unrelated to trauma

• scans performed on patients under the age of 18

• CTC scans without radiologic interpretation

• Previously undergone a CTC during the same hospitalization, only the first CTC was included

Related Conditions & MeSH terms

• Computed Tomography
• Craniocerebral Trauma
• Wounds and Injuries

Locations

Country	Name	City	State
Denmark	Odense University Hospital	Odense	Region Syddanmark

Sponsors (1)

Lead Sponsor	Collaborator
University of Southern Denmark

Country where clinical trial is conducted

Denmark, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Other	30-day mortality and readmission rate	We aim to evaluate the 30-day mortality and readmission rates to a hospital following CTC performed in the ED.	1 year
Other	Neurological intervention	The need for neurological intervention was defined as within 7 days requiring 1) neurosurgical intervention (e.g., craniotomy, hematoma evacuation, elevation of skull fracture, intracranial pressure monitoring, or intubation for head injuries indicated on CT) or 2) neuroradiological intervention (e.g., thrombectomy or intravascular embolization).	1 year
Primary	Positive CTC	Calculate the prevalence of positive CTC findings and to subdivide them to explore potential correlations with biochemical, clinical, and patient baseline variables.; The CT scan was acknowledged as positive if the final radiologic interpretation of all imaging studies reported one or more listed radiological findings: Epidural hematoma; Subdural hematoma; Subarachnoid hematoma; Intraparenchymal hematoma (IPH); Intraventricular hematoma; Fossa posterior hematoma; Acute infarct or dense artery sign; Mass effect or sulcal effacement; Signs of herniation; Basal cistern compression or midline shift; Cerebral contusion; Depressed skull fracture; Diastatic skull fracture; Pneumocephalus; Cerebral edema; Diffuse axonal injury; Tumor; Intracranial infection; Other which resulted in hospitalization	1 year
Secondary	Scandinavian Neurotrauma Committee clinical practice guideline evaluation	We wanted to analyze our use of SNC CPG and evaluate if a more stringent application could reduce the potentially unnecessary overuse of CTC	1 year