Complications; Cesarean Section Clinical Trial
Official title:
Use of Intrathecal Fentanyl and Development of Hyperalgesia in Patients Undergoing Elective Cesarean
Opioid analgesic drugs are the main treatment of patients during anesthesia. Although highly
effective, their use is not without problems. One is the increasing requirement of these
address the same nociceptive stimulus.
Opioid induced hyperalgesia could be an explanation studies in animal models. Through
mechanisms where N-methyl-D-aspartate receptors, glutamatergic system disturbances and
changes in intracellular calcium regulation involved.
The hyperalgesia induced by intrathecal opioids is controversial. The investigators propose
a model study in patients undergoing cesarean section to study the secondary hyperalgesia
induced based on the study of nociceptive thresholds with two methods opioids: Von Frey
filaments and digital algometer.
If intrathecal fentanyl is used in spinal anesthesia for elective cesarean section, then, an
increase in sensitivity will occur. This increase can be measured by von Frey filaments,
expressed in increased requirement clinically opioids.
n/a
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Treatment
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT03052699 -
Medium and Long-term Complications of the Patients Having Had a Vaginal Caesarian in Hospital René Dubos
|
N/A | |
| Completed |
NCT01412073 -
Control of Blood Loss During Caesarean Section
|
Phase 3 | |
| Completed |
NCT01851187 -
Effect of Perinatal Emotional Management on Maternal Emotion and Delivery Outcomes
|
N/A | |
| Completed |
NCT01890720 -
Incisional Negative Pressure Wound Therapy for Prevention of Postoperative Infections Following Caesarean Section
|
N/A | |
| Completed |
NCT02542748 -
Comparison of Norepinephrine and Ephedrine on Hypotension After Spinal Anesthesia in Parturients
|
N/A | |
| Enrolling by invitation |
NCT02694653 -
Preoperative Cesarean Section Intravenous Acetaminophen and Postoperative Pain Control
|
Phase 1 | |
| Completed |
NCT01723605 -
Insitu Repair Versus Uterine Exeriorization During Cesarean Section
|
Phase 3 | |
| Withdrawn |
NCT01516697 -
Non-invasive Cardiac Output Monitoring in Obstetric Patients
|
Phase 4 | |
| Completed |
NCT01741610 -
Fluid Coloading and the Incidence of Hypotension
|
Phase 4 | |
| Terminated |
NCT02838017 -
Tissue Adhesive vs. Sterile Strips After Cesarean Delivery
|
N/A | |
| Completed |
NCT02587013 -
Comparison of Uterine Repair Methods for Cesarean Delivery
|
N/A | |
| Terminated |
NCT02036697 -
Hemodynamic Effects of Low Dose Spinal Anesthesia for Cesarean Section
|
N/A | |
| Recruiting |
NCT01954719 -
Is Routine Cervical Dilatation Necessary During Elective Caesarean Section? A Randomised Controlled Trial
|
N/A | |
| Terminated |
NCT02799667 -
Do Single Use Negative Pressure Dressings Reduce Wound Complications in Obese Women After Cesarean Delivery
|
N/A | |
| Completed |
NCT02459093 -
Subcuticular Suture for Cesarean Skin Incision Closure
|
Phase 4 | |
| Completed |
NCT01858467 -
Supreme LMA and Endotracheal Intubation Use in Caesarean Section
|
N/A | |
| Completed |
NCT01891006 -
Intervention for Postpartum Infections Following Caesarean Section
|
N/A | |
| Withdrawn |
NCT02893696 -
Extra Sitting Time After Spinal Anesthesia for Cesarean Section and Fetal Well-being
|
N/A | |
| Completed |
NCT02785094 -
Education and Social Media Versus Non-Indicated Caesarean Section Rate in Egypt
|
N/A | |
| Completed |
NCT02332278 -
Early Oral Feeding Versus Traditional Postoperative Care After Cesarean Section.
|
N/A |