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SEMS Placement Followed by Chemotherapy and Surgery for Obstructing Left-sided Colonic Cancer

Complication of Treatment Clinical Trial

Official title:
Self-expanding Metallic Stent Placement Followed by Neoadjuvant Chemotherapy and Scheduled Surgery for Treatment of Obstructing Left-sided Colonic Cancer

Clinical Trial Summary

This study aimed to evaluate the safety and feasibility of SEMS followed by neoadjuvant chemotherapy prior to elective surgery for obstructing left-sided colon cancer.

Clinical Trial Description

Stoma is reported to be frequent in self-expanding metallic stent (SEMS) treated patients with obstructing left-sided colon cancer than in those with non-obstructing surgery. Retrospective study reported worse overall survival with SEMS and elective surgery than with emergency surgery in patients with left-sided malignant colon obstruction. In practice, intestinal wall edema following stent placement increases the difficulty of surgery, and this could be a major problem if the interval between stent insertion and surgery is short (1-2 weeks). The patients with obstructing left-sided colon cancer received SEMS treatment, and the recevied neoadjuvant chemotherapy prior to elective surgery. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04039360
Study type Observational
Source Beijing Chao Yang Hospital
Contact
Status Completed
Phase
Start date May 1, 2014
Completion date November 30, 2015
View Details
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