Complication of Hemodialysis Clinical Trial
Official title:
Effects of Simple Sodium Alignment on Short-, Medium- and Long-term Clinical and Laboratory Outcome Measures
Verified date | February 2016 |
Source | Renal Research Institute |
Contact | n/a |
Is FDA regulated | No |
Health authority | United States: Institutional Review Board |
Study type | Observational |
A difference between dialysate and serum sodium concentration leads to diffusive sodium transfer across the dialyzer membrane. The consequences of diffusive sodium flux into the patient can be chronic sodium overload leading to overhydration, hypertension, cardiovascular disease, and other problems. Diffusive sodium flux out of the patient can lead to intradialytic blood pressure instability. A simple strategy for alignment of dialysate and serum sodium concentrations was implemented starting in April/May 2010 in order to minimize the problems particularly associated with chronic sodium overload.
Status | Completed |
Enrollment | 148 |
Est. completion date | August 2014 |
Est. primary completion date | August 2014 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 18 Years to 88 Years |
Eligibility |
Inclusion Criteria: - Subjects on hemodialysis Exclusion Criteria: |
Observational Model: Cohort, Time Perspective: Retrospective
Country | Name | City | State |
---|---|---|---|
United States | Renal Research Institute | New York | New York |
Lead Sponsor | Collaborator |
---|---|
Renal Research Institute |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Other | Body weight | Each treatment (3x per week)- 2 years of treatment data | No | |
Other | Serum electrolytes | Each treatment (3x per week)- 2 years of treatment data | No | |
Other | Intradialytic saline administration | Per occurance | No | |
Other | Inflammatory markers | Each treatment (3x per week)- 2 years of treatment data | No | |
Other | Medications | Per occurance | No | |
Other | Missed treatments | Per occurance | No | |
Primary | Interdialytic weight gain | Each dialysis treatment (3x per week) - 2 years of treatment data | No | |
Primary | Pre-dialysis Blood Pressure | Each dialysis treatment (3x per week)- 2 years of treatment data | No | |
Secondary | Hospitalization rate and number of days | Per occurence during the entire follow-up period of 2 years | No |
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT02263196 -
The Efficacy of Alcohol After Betadine and Combination of Alcohol and Betadine on Inflammation Vascular Access
|
Phase 1/Phase 2 | |
Completed |
NCT01396980 -
Microcirculation During Haemodialysis
|
N/A | |
Completed |
NCT02513303 -
Trial to Evaluate the Sirolimus-Eluting Collagen Implant on AV Fistula Outcomes
|
Phase 3 | |
Completed |
NCT02443376 -
The Effects of Hemodialysis Session on Vascular Stiffness
|
N/A | |
Completed |
NCT02558153 -
RCT of Paclitaxel DEB Compared to Standard PTA in Dialysis Fistula
|
N/A | |
Completed |
NCT00322322 -
Early Administration of L-carnitine in Hemodialysis Patients
|
Phase 3 | |
Completed |
NCT02870829 -
Treatment to Reduce Vascular Calcification in Hemodialysis Patients Using Vitamin K
|
Phase 2 | |
Completed |
NCT00501956 -
Intradialytic Parenteral Nutrition in Hemodialysis Patients
|
Phase 4 | |
Completed |
NCT02950389 -
REmoval of Free Light Chains. A COmpaRison of Three Different dialyzERs
|
N/A | |
Recruiting |
NCT02446535 -
Probing the Dry Weight (DW) by Bioimpedance (BIA): Which is the Gold Standard Between Clinical DW and BIA DW?
|
N/A | |
Completed |
NCT00568399 -
Sodium Thiosulfate Treatment of Vascular Calcification in ESRD
|
N/A | |
Recruiting |
NCT05425056 -
A Study Testing the Use of a Perivascular Sirolimus Formulation (Sirogen) in ESRD Patients Undergoing AV Fistula Surgery
|
Phase 3 | |
Completed |
NCT01278693 -
Effect of Oral L-carnitine Supplement on Lipid Profile, Anemia, and Quality of Life of Patients
|
Phase 2 | |
Completed |
NCT00732069 -
Study of Inflammation and Oxidative Stress in Persons Undergoing Dialysis
|
Phase 2 | |
Completed |
NCT01147354 -
Effect of Selenium Supplementation on Inflammatory,Oxidative and Nutritional Markers in Hemodialysis Patients
|
Phase 3 | |
Completed |
NCT02747966 -
The Relationship Between the Flow of Arteriovenous Fistula and Cardiac Function in Haemodialysis Patients
|
N/A |