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Complication of Anesthesia clinical trials

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NCT ID: NCT02299063 Recruiting - Clinical trials for Complication of Anesthesia

Dexmedetomidine Effect on Mitochondrial Function

Start date: November 2014
Phase: Phase 4
Study type: Interventional

The investigators hypothesize that in addition to a known sympatholytic effect, intraoperative dexmedetomidine reduces adverse changes in mitochondrial function and structure attenuating ischaemia-reperfusion and end-organ injury for children with non cyanotic congenital heart defects having corrective heart surgery.

NCT ID: NCT02041806 Recruiting - Clinical trials for Complication of Anesthesia

Assessing Peripheral Nerve Block Scoring Systems for Intra-Operative and Post-Operative Analgesia

Start date: July 2013
Phase: N/A
Study type: Observational

The purpose of this study is to determine if Peripheral Nerve Block scoring systems are effective in predicting the achievement of intra-operative anaesthesia and post-operative analgesia.

NCT ID: NCT01960543 Completed - Clinical trials for Complication of Anesthesia

Effects of Bupivacaine and Levobupivacaine on Cerebral Oxygenation During Intrathecal Anesthesia in Elderly Patients

Start date: October 2013
Phase: Phase 4
Study type: Interventional

Elderly patients with hip fracture are frail due to associated comorbidity. In these situations, regional anesthesia is recommended as it is associated to less postoperative cognitive dysfunction. However, hypotension during the process may impair ischemic cardiopathy and induce a cerebrovascular stroke. Selection of the right anesthetic agent and the administration of vasoactive drugs during the process can minimize these risks. Although bupivacaine and levobupivacaine share pharmacokinetic and pharmacodynamic properties, the studies show conflicting results. The aim of this study is to investigate if there are clinically relevant differences between these two drugs in terms of hemodynamic parameters during the surgical process with special focus on the effects on regional cerebral oximetry and cognitive status after surgery.

NCT ID: NCT01958138 Completed - Clinical trials for Complication of Anesthesia

Isoflurane Versus Propofol for Removal of LMA in Children

Start date: April 2012
Phase: Phase 2/Phase 3
Study type: Interventional

The study will be done in paediatric patients by comparing two different techniques of Laryngeal Mask Airway (LMA) removal under deep anesthetic plane. The both study techniques will be compared for safe LMA removal on the basis of adverse airway events and emergence time duration and recovery room stay timing.