Complex Symptom Disorders Clinical Trial
Official title:
Multidisciplinary Return-to-work Rehabilitation and Return-to-work Follow-up, a Randomized Study of Patients With Complex Symptom Disorders
The large number of people on long-term sick leave is a major public health concern in
Norway. The main causes of disability are musculoskeletal and mental disorders. Long-term
sick leave causes a decline in individual life-quality, is associated with increased risk for
mental disorders and represents a very large cost for the Norwegian society.
The purpose of this study is to determine whether the patients included return to work after
rehabilitation at Hysnes Rehabilitation Centre. This includes an investigation of what is
considered to be the effect of Return-to-work rehabilitation measured before, during and
after the stay at the rehabilitation centre:
The study specifically looks at the effect of structured and standardized return-to-work
follow up of the patient, including contact with stakeholders (general practitioner, social
security office and workplace).
In addition there is a need to describe the patients participating in the program. The
aetiology of complex symptom disorders is poorly understood and the role of genetics and
stress is not translatable to a complex symptom population. This complicates the transition
from current biological research to a clinical use regarding these patients. If the
investigators can assist in understanding how these patients, who are multiusers of health
care and have received sickness benefit for a long time, develop their disorders and
symptoms, it will be of great importance to the Norwegian community. Therefore the study
consists of multimodal measurements of the patients before, during and after a rehabilitation
programme at Hysnes Rehabilitation Centre. These measures include genotype, saliva cortisol,
medical-, psychological-, physiological diagnostics and work related factors.
Related aims:
Investigate if multidisciplinary treatment based on acceptance and commitment therapy,
contributes to normalisation of cortisol release with regards to a standardized stress test.
See wether individual differences regarding the stress profile can predict return to work in
patients with complex symptom disorders.
Investigate genetic risk factors in relation to Return to Work rehabilitation and identify
treatment moderators in a multidisciplinary rehabilitation program.
n/a