Changes in the Permeability of the Blood Brain Barrier and Intestinal Barrier in Humans During Conditions of Stress and Immune Activation: in Vivo Studies

Combat Training Stress Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01417416
• Other study ID #: C/08/236
• Secondary ID: DSOCL08210
• Status: Completed
• Phase: N/A
• First received: August 15, 2011
• Last updated: August 15, 2011

Study information

• Verified date: February 2009
• Source: National University Hospital, Singapore
• Contact: n/a
• Is FDA regulated: No
• Health authority: Singapore: Domain Specific Review Boards
• Study type: Observational

Clinical Trial Summary

The relevance of BBB and IB permeability changes as a major precipitating cause for cognitive and digestive dysfunction in the military stress setting.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 0
• Gender: Male
• Age group: 18 Years to 50 Years

Eligibility

Inclusion Criteria:

• Healthy male troops (aged 18-50 yrs) scheduled to be engaged in a protracted multi-day stressful field exercises.

Exclusion Criteria:

• Significantly systemic disease, including cardiovascular, psychiatric, neurological (including polyneuropathies) and endocrine disease including diabetes mellitus.

• No written informed consent obtained from subject.

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

• Combat Training Stress

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
National University Hospital, Singapore