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Intermittent Cefoxitin Administration Versus Loading Bolus Followed by Continuous Infusion for the Prevention of Surgical Site Infection in Colorectal Surgery — PROPHYLOXITIN  

Colorectal Surgery Clinical Trial

Official title:
Intermittent Cefoxitin Administration Versus Loading Bolus Followed by Continuous Infusion for the Prevention of Surgical Site Infection in Colorectal Surgery: a Multicentre, Double-blind, Randomized Controlled Clinical Trial

Clinical Trial Summary

The goal of this prospective, multicentre, double-blind, randomized clinical trial is to compare intermittent cefoxitin administration to loading bolus followed by continuous infusion for surgical antibiotic prophylaxis in colorectal surgery. The main objective is to demonstrate the superiority of a loading dose of cefoxitin followed by continuous infusion over standard of care boluses in reducing SSI within 30 days after colorectal surgery

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05755789
Study type Interventional
Source Poitiers University Hospital
Contact Matthieu BOISSON, MD-PhD
Phone +33549444635
Email matthieu.boisson@chu-poitiers.fr
Status Recruiting
Phase Phase 3
Start date June 22, 2023
Completion date June 2025
View Details
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