Colorectal Neoplasms Clinical Trial
Official title:
A Prospective Observational Cohort Study Evaluating Resection Rate in Patients With Metastatic Colorectal Cancer Treated With Aflibercept in Combination With FOLFIRI - Observatoire résection
Primary Objective: -Evaluate the resection rate (R0/R1) in current practice for aflibercept in combination with irinotecan plus 5-fluorouracil (FOLFIRI) in patients treated for metastatic colorectal cancer (mCRC) after failure of an oxaliplatin-containing regimen Secondary Objectives: - Evaluate overall survival, progression-free survival and relapse-free survival. - Evaluate conversion rates (initially unresectable disease which became resectable after chemotherapy, with R0/R1 resection). - Evaluate histological and radiological response rates. - Evaluate rate of postoperative complications. - Evaluate safety.
The estimated inclusion period is 45 months. Patient follow-up is 24 months and the total study duration is 69 months. Last patient status (alive or dead) collected before database lock. ;
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