Colorectal Neoplasms Clinical Trial
Official title:
ChronoFOLFOX Plus Avastin for Patients With Metastatic Colorectal Cancer
To determine efficacy in the delivery of chronomodulated chemotherapy.
The purpose of this study is to determine if treatment with 5-Fluorouracil, leucovorin,
oxaliplatin, and Avastin will cause colorectal tumor cells to shrink or disappear. The study
will also determine the safety of these drugs when given together and the quality of life of
the patients who are enrolled in the study.
It is thought that these drugs will be better tolerated if they are chronomodulated, i.e.,
if they are given at certain times of day rather than as a continuous infusion.
;
Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
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