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Colorectal Carcinoma clinical trials

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NCT ID: NCT04108481 Suspended - Rectal Cancer Clinical Trials

Immunotherapy With Y90-RadioEmbolization for Metastatic Colorectal Cancer

iRE-C
Start date: October 5, 2020
Phase: Phase 1/Phase 2
Study type: Interventional

This clinical trial will be conducted as a single-center, open-label, Phase I/2 trial to evaluate the feasibility and safety of Yttrium-90 radioembolization (Y90-RE) in combination with a fixed dose of of immunotherapy (durvalumab - 750 mg) in subjects with liver-predominant, metastatic colorectal cancer (mCRC), which is mismatch repair proficient/microsatellite stable (pMMR/MSS).