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Clinical Trial Summary

There is pre-existing evidence that probiotics could be useful in the improvement of ileus rates. One metaanalysis of 30 studies demonstrated a reduction in the prevalence of post-operative ileus as determined by time to flatus, time to defecation, as well as postoperative abdominal distension (PMID:37373843). More broadly in gastrointestinal surgery, a meta-analysis of 21 randomised controlled trials similarly affirmed the speedier recovery of gastrointestinal function after surgery when probiotics were administered (PMID: 35231076). In spite of these advantages, the routine use of probiotics perioperatively for colorectal cancer surgery is not performed in Singapore. We therefore seek to perform a trial to investigate whether probiotic administration perioperatively may reduce post operative ileus rates.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT06456229
Study type Interventional
Source National University Hospital, Singapore
Contact Dedrick Chan, MBBS, DPhil
Phone 67795555
Email surckhd@nus.edu.sg
Status Recruiting
Phase N/A
Start date July 1, 2024
Completion date May 1, 2025

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