Risk Factors of Venous Thromboembolism After Colorectal Cancer Surgery

Colorectal Cancer Clinical Trial

Official title:

Risk Factors of Venous Thromboembolism After Colorectal Cancer Surgery

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT06302179
• Other study ID #: 140-14/24
• Status: Completed
• Start date: January 2015
• Est. completion date: May 2023

Study information

• Verified date: March 2024
• Source: Pirogov Russian National Research Medical University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Aim of our study is to find frequency and identify risk factors for venous thromboembolism development in patients who underwent surgery for colorectal cancer. There were 137 patients enrolled in our retrospective observational cohort study. Included patients were operated for incisional hernia in Saveljev University Surgery Clinic from January 2016 to December 2017. Compression duplex ultrasound of lower legs veins was performed in 2-14 days after surgery for all participants. The primary endpoint was the occurrence of the venous thromboembolism event, including pulmonary embolism.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 137
• Est. completion date: May 2023
• Est. primary completion date: December 2017
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

operated for incisional hernia in Saveljev University Surgery Clinic. No Exclusion Criteria

Related Conditions & MeSH terms

• Colorectal Cancer
• Colorectal Neoplasms
• Thromboembolism
• Venous Thromboembolism

Locations

Country	Name	City	State
Russian Federation	Pirogov Russian National Research Medical University	Moscow

Sponsors (1)

Lead Sponsor	Collaborator
Pirogov Russian National Research Medical University

Country where clinical trial is conducted

Russian Federation, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Venous Thromboembolism	Screening ultrasound in the postoperative period was aimed at looking for signs of deep vein thrombosis. The imaged vessels included the common femoral, great saphenous, superficial femoral, deep femoral, popliteal, posterior tibial, and peroneal veins of both lower extremities. The presence of a thrombotic process in the vein was evidenced by the rigidity of its walls during compression by the sensor, the presence of hyperechoic inclusions, and the impossibility of visualizing blood flow during color mapping.	was performed with median 4 days (min 2 day, max 14 days, interquartile range 2-5 days) after surgery