Colorectal Cancer Clinical Trial
Official title:
64Cu/68Ga Labelled EB-ss-CPT PET/CT Scan in Colorectal Cancer
Positron labeled camptothecin based PET imaging is a new imaging technique that uses positron isotopes such as 68Ga/64Cu for PET/CT (MR) imaging. It is expected to have significant clinical significance in staging and detecting primary and metastatic head and neck cancer, oral cancer, and colorectal cancer tumors.
Status | Recruiting |
Enrollment | 10 |
Est. completion date | August 31, 2023 |
Est. primary completion date | August 31, 2023 |
Accepts healthy volunteers | No |
Gender | All |
Age group | N/A to 85 Years |
Eligibility | Inclusion Criteria: - In the near future (within 2 months), patients who plan to undergo puncture biopsy or undergo tumor surgical treatment or are clinically highly suspected of cancer (including primary and tumor recurrence and metastasis) - Able to understand and voluntarily sign informed consent forms, with good compliance Exclusion Criteria: - Severe abnormalities in liver and kidney function - Suffering from claustrophobia or other mental illnesses - Pregnant, pregnant, and lactating women |
Country | Name | City | State |
---|---|---|---|
China | Chinese Academy of Medical Science & Peking Union Medical College Hospital | Beijing | Beijing |
Lead Sponsor | Collaborator |
---|---|
Peking Union Medical College Hospital |
China,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Dosimetric distribution of radiopharmaceuticals | Input the data of 5-6 patients into HERMES software, and analyze the dose distribution of radioactive drugs in human body through HERMES software | 2 months | |
Primary | Standardized uptake value | The semiquantitative analysis will be performed by the same person for all the cases, and the standardized uptake value (SUV) of the tracer in breast tumor will be measured. SUV were obtained by a self-made software and referring to phantom study.If the SUV value cannot be obtained, the COUNTS of target organ/background ratio between the lesion and surrounding tissues shall be used for calculation. | 1 year | |
Secondary | Adverse events collection | Adverse events within 1 week after the injection and scanning of patients and patients will be followed and assessed | 1 year |
Status | Clinical Trial | Phase | |
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