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NCT04976439 Clinical Trial

Patogenic Mutation in 5 Genes

Colorectal Cancer Clinical Trial

Official title:
Genomic Landscape of APC, KRAS, TP53, PIK3CA, and MLH1 in Colorectal

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT04976439
Other study ID # MUTASICRC
Secondary ID
Status Completed
Phase
First received
Last updated
Start date May 1, 2021
Est. completion date June 14, 2021

Study information
Verified date July 2021
Source Dr Cipto Mangunkusumo General Hospital
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

This is a pathogenic mutation profile of colorectal patients specifically in 5 genes, i.e. APC, TP53, PIK3CA, KRAS, and MLH1. Single nucleotide variants identified were synchronized with patients' characteristics.

Recruitment information / eligibility
Status Completed
Enrollment 22
Est. completion date June 14, 2021
Est. primary completion date June 10, 2021
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - FFPE samples fullfilling purity criterion and pass quality control Exclusion Criteria: - none

Study Design

Related Conditions & MeSH terms

Intervention

Other:
• co-occuring mutation
APC, TP53, PIK3CA, KRAS APC, TP53, PIK3CA, MLH1 APC, TP53, PIK3CA, KRAS, and MLH1 APC, TP53, PIK3CA

Locations
Country Name City State
Indonesia Vania Myralda Giamour Marbun Jakarta ALL

Sponsors (1)
Lead Sponsor Collaborator
Dr Cipto Mangunkusumo General Hospital

Country where clinical trial is conducted

Indonesia, 

Outcome
Type Measure Description Time frame Safety issue
Primary Description of clinical characteristics Age, gender January 2017 - June 2021
Primary Description of tumor nature grade, stage, lymphovascular invasion, tumor location January 2017 - June 2021
Primary Description of survival Median of life expectancy January 2017 - June 2021
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