Colorectal Cancer Clinical Trial
Official title:
Research on New Technologies for Screening and Early Diagnosis of Malignant Tumors - Establishment and Clinical Validation of New Technologies for Accurate Screening of Colorectal Cancer Based on Multi-omics
NCT number | NCT04913233 |
Other study ID # | 2021-0199 |
Secondary ID | |
Status | Not yet recruiting |
Phase | |
First received | |
Last updated | |
Start date | July 2021 |
Est. completion date | November 2024 |
Background: The current screening techniques for colorectal cancer include colonoscopy, fecal occult blood, and high-risk factor questionnaires. However, the colorectal cancer screening technology that has been widely used at present cannot take into account sensitivity and specificity, and the tumor detection rate is low. The purpose of research: 1. Build a new type of population colorectal cancer precision screening technology program; 2. Improve the detection rate of colorectal cancer in the population by new methods (compared with the existing domestic advanced technology) by ≥20%, and improve the specificity of colorectal cancer screening by ≥15% without significantly reducing the sensitivity.
Status | Not yet recruiting |
Enrollment | 9000 |
Est. completion date | November 2024 |
Est. primary completion date | June 2024 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 40 Years to 74 Years |
Eligibility | Inclusion Criteria: Age: 40-74 years old Exclusion Criteria: 1. Combine severe disorders to make it unsuitable for colonoscopy 2. Combine other tumors 3. Mental and behavioral abnormalities do not cooperate with the screener 4. Researchers believe that other reasons are not suitable for enrollment |
Country | Name | City | State |
---|---|---|---|
China | Chinese Medicine Hospital of Haining City, Haining Cancer Preventional and Treatment Research Institute | Haining | Zhejiang |
China | Jiashan County Cancer Prevention and Treatment Institute | Jiashan | Zhejiang |
China | Lanxi City People's Hospital, Linjiang Hospital | Lanxi | Zhejiang |
Lead Sponsor | Collaborator |
---|---|
Second Affiliated Hospital, School of Medicine, Zhejiang University |
China,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Colorectal cancer detection rate in the population | Colorectal cancer detection rate in the population | through study completion, an average of 3 years | |
Primary | Colorectal cancer screening specificity | Colorectal cancer screening specificity | through study completion, an average of 3 years | |
Primary | Colorectal cancer screening sensitivity | Colorectal cancer screening sensitivity | through study completion, an average of 3 years |
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