Colorectal Cancer Clinical Trial
Official title:
Evaluation and Mechanism of Strengthening the Spleen and Reducing Phlegm Method in Improving Radical Resection Rate of Colorectal Cancer
This study will take disease-free survival time and recurrence and metastasis rate as the main evaluation indexes, to evaluate the clinical efficacy of strengthening the spleen and reducing phlegm method in patients with stage II high-risk and stage III colorectal cancer
The study enrolled 350 patients with stage II high-risk and stage III colorectal cancer who
underwent adjuvant chemotherapy (based on a 5-fluorouracil(5-FU) regimen for at least 3
months) and patients who received chemotherapy for less than 3 months. The study will use a
large sample, multicenter, randomized, double-blind study. The experimental group was given
oral Jianpi Huatan dispensing granule, once a day in the morning and evening, 1 course per 1
month, a total of 3 courses; the control group of oral Chinese medicine formula low dose
control granules (including the test group dose 1 /10), 1 time each morning and evening, 1
course per month, for a total of 3 courses.
The patients were followed up once a month during the treatment period and once every 3-6
months after the end of treatment until the patient relapsed, died or the study was over.Some
patients in the study will be tested for circulating tumor cells.
Main outcome measures is Disease-free survival time(DFS)and Metastasis recurrence rate in 1
year;Secondary outcome measures:Quality of life score: applied quality of life
scale.Metastasis recurrence rate in 2、3years.
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