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Regorafenib Plus 5-Fluorouracil/Leucovorin Beyond Progression in mCRC

Colorectal Cancer Clinical Trial

Official title:
A Pilot Phase II, Single Arm, Open Label, Investigator-initiated Clinical Trial of Regorafenib Plus 5-Fluorouracil/Leucovorin (5FU/LV) Beyond Progression on Regorafenib Monotherapy in Metastatic Colorectal Cancer (mCRC)

Clinical Trial Summary

This is a single arm open label pilot phase II trial of Regorafenib PO plus 5-FU/LV infusion in 15 mCRC patients who progressed on prior Regorafenib monotherapy as well as 5-FU containing chemotherapy combinations.The study will enroll mCRC patients with prior progression on standard multi-agent combination chemotherapy and progression on regorafenib monotherapy.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03099486
Study type Interventional
Source Fox Chase Cancer Center
Contact
Status Terminated
Phase Phase 2
Start date October 6, 2017
Completion date June 2, 2020
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