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Clinical Trial Summary

The aim of this clinical trial is to find out whether Regorafenib and Sintilimab in combination with electroacupuncture works in treating participants with microsatellite stable (MSS) advanced colorectal cancer who have failed one or more second-line standard chemotherapy regimens. It will also learn about the efficacy and safety of the combination therapy. The main questions the trial aims to answer are: Does combination therapy reduce the overall survival time ? What medical problems do people have when they take combination therapy? Participants will Regorafenib, take for 2 weeks and stop for 1 week; Sintilimab, intravenous, every 3 weeks; Electroacupuncture was performed 1 day before, on the day of, and on the 2nd day after each cycle of Sintilimab administration, and patients completed 3 treatments in week 1, followed by 1 treatment per week for 2 weeks, with 5 treatments per dosing


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT06456515
Study type Interventional
Source The First People's Hospital of Changzhou
Contact Wenwei Hu
Phone 13912330886
Email ei1979@163.com
Status Not yet recruiting
Phase N/A
Start date June 2024
Completion date March 2026

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