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Clinical Trial Summary

To determine the maximum tolerated dose (MTD), the recommended phase 2 dose (RP2D) and the toxicity profile (NCI CTCAE v5.0 and immune related adverse events) of i.t. administration of anti-CTLA4 antibody (ipilimumab) and TLR4 agonist (synthetic glucopyranosyl lipid A formulated in a stable emulsion [GLA-SE]) in colorectal LM (CRLM) in combination with intravenous (i.v.) administration of anti-PD-1 antibody (nivolumab) and chemotherapy (FOLFOX regimen).


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT03982121
Study type Interventional
Source Gustave Roussy, Cancer Campus, Grand Paris
Contact
Status Withdrawn
Phase Phase 1
Start date June 4, 2019
Completion date February 12, 2020

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