Colorectal Cancer Metastatic Clinical Trial
— TACEOfficial title:
Raltitrexed and Oxaliplatin and Lipiodol Transcatheter Arterial Chemoembolization for Advanced Colorectal Cancer
To evaluate the efficacy and safety of Raltitrexed for advanced colorectal cancer
Status | Recruiting |
Enrollment | 320 |
Est. completion date | December 2017 |
Est. primary completion date | December 2017 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years to 75 Years |
Eligibility |
Inclusion Criteria: 1. Histologically confirmed colorectal adenocarcinoma 2. Disease limited to the liver Unresectable disease by surgery or other local therapies 3. Age >18 years 4. ECOG performance status 0-2,Child pugh A or B 5. Expected survival = 3 months 6. Adequate hematological, hepatic, and renal function Exclusion Criteria: 1. Pregnant or lactating women 2. Patients with severe organ dysfunction or failure 3. With severe cardiovascular disease, or mental 4. Extraliver metastases |
Country | Name | City | State |
---|---|---|---|
China | Zhongshan Hospital Fudan University | Shanghai | Shanghai |
Lead Sponsor | Collaborator |
---|---|
Nanjing Chia-tai Tianqing Pharmaceutical |
China,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Progression-free survivial | From date of randomization until date of first documented PD, date of death | 8 months after last patient randomized |
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