Laparoscopic Surgery for T4 Tumor of the Colon Cancer (LST4C Trial)

Status Recruiting

Clinical Trial Summary

The purpose of this study is to compare the short- and long-term survival of laparoscopic surgery and conventional open surgery for T4 colon cancer

Clinical Trial Description

The investigators previous study indicated that laparoscopic surgery is feasible in T4 colon cancers with comparable clinical and oncologic outcomes. Laparoscopy can be considered as an alternative approach for T4 colon cancers with the advantage of faster recovery. However, the clinical value of laparoscopic surgery for T4 colon cancer was only validated in some retrospective study and some prospective study in single institute with small sample of patients. The aim of the present study is to compare the short-and long-term survival outcomes of laparoscopic surgery and conventional open surgery for T4 colon cancer as well as the mortality and the morbidity. The number of patients needed to get a 80% power is 1960. The average number of patients/surgical center is approximately 200 in each of 10 surgical centers. The preoperative, intraoperative and postoperative period will be in complete accordance with the usual care of the center. The baseline demographics and conditions as well as the perioperative items and the postoperative occurrences will be recorded through a prior designed equestionnaire.

Systematically analyze and compare the disease free survival rate, the mortality, the morbidity, and the proportion of completion of laparoscopic surgery of the two surgical strategies (laparoscopy VS conventional open surgery). ;

Study Design

Related Conditions & MeSH terms

Colonic Neoplasms

Clinical Trial Details

NCT number	NCT03314896
Study type	Interventional
Source	Fudan University
Contact	Xinxiang Li, MD,PhD
Phone	86-13918176716
Email	lxx1149@163.com
Status	Recruiting
Phase	N/A
Start date	October 2016
Completion date	October 2024

View Details

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