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Establishing Effective Screening Methods for Diagnosing Hereditary Nonpolypoisis Colorectal Cancer

Colonic Neoplasms Clinical Trial

Official title:
Establishing Effective Screening Methods for Diagnosing Hereditary Nonpolypoisis Colorectal Cancer

Clinical Trial Summary

Correct identification of Lynch syndrome at the time of colorectal cancer presentation is important. We aim to find best ways to screen patients with colorectal cancer in Korea.

Clinical Trial Description

Patients with newly diagnoised colorectal cancer will be eligible. They will undergo detailed history taking including family history, and molecular stuidies including microsatellite instability test and immunohistochemistry for DNA mismatch repair protein with pre-selection. Any abnormal finding in molecular stuides will be offered genetic testing (after testing methylation status for patients with abnormalities in MLH1). ;

Study Design

Observational Model: Defined Population, Primary Purpose: Screening, Time Perspective: Longitudinal

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00516230
Study type Observational
Source Samsung Medical Center
Contact Dong Kyung Chang, M.D. Ph.D
Phone +82-2-3410-3409
Email dkchang@skku.edu
Status Recruiting
Phase N/A
Start date January 2006
Completion date December 2011
View Details
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